Berberine is a constituent of some plants including Barberry (Berberis vulgaris), Oregon Grape (Berberis aquifolium), and Goldenseal (Hydrastis canadensis). Berberine Complex contains extracts of berberine-containing plants: barberry, Oregon grape, and goldenseal. In addition to berberine, Goldenseal extract also contains other alkaloids such as hydrastine. Traditional use of herbs and extracts often rely on the complex nature of plants rather than isolated bioactive compounds. Berberine Complex is intended for traditional gastrointestinal support.